Drugs Not Included in Groups A - C and Rationale for Non-inclusion

 Rationale for Grouping of Anti-TB Drugs

Drugs Used in the Management of Adverse Events

The State Drug Store (SDS) shall constitute drug boxes for:

1. Shorter oral Bedaquiline (Bdq)-containing Multi-drug resistant (MDR)/ Rifampicin-resistant Tuberculosis (RR-TB) regimen (Type A and B)
2. Longer oral Multi (M)/ Extensively Drug-resistant Tuberculosis (XDR-TB) regimen
3. Isoniazid (H) mono/ poly DR-TB regimen

Boxes will be prepared manually only and not through Nikshay Aushadhi software.

From Nikshay Aushadhi drugs will be supplied in loose to districts.

Loose drugs will be supplied to the Nodal (N)/ District DR-TB Centre (DDR-TBC) from the State Drug Stores (SDS)/ District Drug Stores (DDS) as per the consumption pattern of the previous month and requested via Nikshay Aushadhi.

Standard Patient-wise Boxes (PWBs) are constituted for TB patients initiated on Isoniazid (H) Mono/ Poly Drug-resistant TB (DR-TB) regimen. 

This regimen has no segregation in terms of Intensive Phase (IP) or Continuation Phase (CP), hence drugs are provided in a single type of PWB. 

Table: Constituents of standard PWB (6 months) of H mono/ poly DR-TB regimen; Source: Guidelines for PMDT, India 2021, p134

Role of the State Drug Store [SDS] in the Constitution of Patient-wise Boxes 

Guidelines for Issuing Bedaquiline and Delamanid to the Patient

Constituents of Patient-wise Boxes [PWB] for Isoniazid [H] Mono/Poly DR-TB Regimen

Patients who are “lost to follow-up” (interrupt treatment continuously for 2 months or more) and return back for Drug-resistant TB (DR-TB) treatment under National TB Elimination Programme (NTEP):