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Second Line LPA [SLLPA]

Second-line Line Probe Assay (SL-LPA) is a LPA to detect resistance to the second-line anti-TB drugs. This test is recommended for identifying TB patients with Multidrug-resistance (MDR) or rifampicin-resistance and those who can be placed on the shorter MDR-TB regimen.

 

The SL-LPA produces results in just 24-48 hours.

 

Truenat MTB and RIF Assay as a TB Diagnostic Test

 

The tests are performed using Trueprep AUTO Sample Pre-treatment and Prep kits and Truenat micro-PCR chips.

 

To detect M. tuberculosis, the Truenat MTB chip amplifies a portion of the ribonucleoside-diphosphate reductase gene, nrdB with a Limit of Detection (LOD) of about 100 Colony Forming Units (CFU)/ml sputum sample.

 

DNA extraction and detection of M. tuberculosis takes approximately one hour.

 

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