Types of Drug Resistance Tuberculosis -DRTB

Resistance to Fluroquinolone (FQ)

• Ofloxacin,
• Levofloxacin,
• Moxifloxacin

Resistance to Group A Drugs

• Bedaquiline or
• Linezolid

H Mono / Poly Drug Resistance

• ​Resistant to Isoniazid (H)
• Sensitive to Rifampicin (R)
• Unknown / Sensitive to Fluoroquinolone (FQ) or Group A Drugs - Bedaquiline or Linezolid

Rifampicin Resistance (RR)

• Resistant to Rifampicin (R)
• Unknown / Sensitive to other drugs

Multi Drug Resistance TB (MDR TB)

• Resistant to Isoniazid (H) and Rifampicin (R)
• Unknown / Sensitive to Fluoroquinolone (FQ) or Group A Drugs - Bedaquiline or Linezolid

Pre-Extensive Drug Resistance (Pre -XDR)

• Resistant to Isoniazid (H), Rifampicin (R) and any Fluroquinolone (FQ)

• Sensitive/ Unknown to Group A Drugs - Bedaquiline or Linezolid

Extensive Drug Resistance (XDR)

• Resistant to Isoniazid (H) , Rifampicin (R) and any Fluoroquinolone (FQ) and at least one additional Group A Drugs - (presently to either Bedaquiline or linezolid [or both])