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Types of monthly PWB
Learning ObjectivesType A and Type B. Table to mention about the regimen
There are two types of monthly Patient Wise Boxes (PWB) issued to the TB patients.
1) Type A: Contains oral drugs that are used for treatment during both the Intensive Phase (IP) and Continuation Phase (CP).
2) Type B: Contains injectables which are prescribed for Intensive Phase (IP) only
Based on the regimen and weight band of the patients , PWB are prepared and issued to the patients.
Contents of PWB
- PWB for Shorter Oral Bedaquiline-containing MDR/RR-TB Regimen: Constitutes both Type A and Type B box
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Type A box |
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Use in Intensive Phase (IP) as well as Continuation Phase (CP) |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
|
Tab. Levofloxacin* |
250/ 500 mg |
250 mg *30 tab |
250 mg *30 tab + 500 mg *30 tab |
500 mg *60 tab |
500 mg *60 tab |
|
Tab. Clofazimine |
50/ 100 mg |
50 mg *30 tab |
100 mg *30 tab |
100 mg *20 tab |
100 mg *60 tab |
|
Tab. Ethambutol |
400/ 800 mg |
400 mg *30 tab |
800 mg *30 tab |
400 mg *30 tab + 800 mg *30 tab |
600 mg *60 tab |
|
Tab. Pyrazinamide |
500/ 750 mg |
750 mg *30 tab |
500 mg *30 tab + 750 mg *30 tab |
500 mg *60 tab + 750 mg *30 tab |
500 mg *30 tab + 750 mg *60 tab |
|
Tab. Pyridoxine |
50/100 mg |
50 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
* When moxifloxacin is prescribed under exceptional conditions instead of levofloxacin, the modified box with moxifloxacin (normal dose) can be prepared from the standard box at DDS.
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Type B box |
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Use in IP |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
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Tab. Isoniazid |
100/ 300 mg |
300 mg *30 tab |
300 mg *60 tab |
300 mg *90 tab |
300 mg *90 tab |
|
Tab. Ethionamide |
125/ 250 mg |
125 mg *30 tab + 250 mg *30 tab |
250 mg *60 tab |
250 mg *90 tab |
250 mg *120 tab |
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Bedaquiline bottle |
100 mg |
Jar of 188 tablets for full course |
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- PWB for Shorter Injectable-containing Regimen: Constitutes both Type A and Type B box
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Type A box |
|
Use in Intensive Phase (IP) as well as Continuation Phase (CP) |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
|
Tab. Moxifloxacin-High Dose |
400 / 800 mg |
400 mg *30 tab |
400 mg *30 tab |
400 mg *60 tab |
400 mg *60 tab |
|
Tab. Clofazimine |
50/ 100 mg |
50 mg *30 tab |
100 mg *30 tab |
100 mg *20 tab |
100 mg *60 tab |
|
Tab. Ethambutol |
400/ 800 mg |
400 mg *30 tab |
800 mg *30 tab |
400 mg *30 tab + 800 mg *30 tab |
600 mg *60 tab |
|
Tab. Pyrazinamide |
500/ 750 mg |
750 mg *30 tab |
500 mg *30 tab + 750 mg *30 tab |
500 mg *60 tab + 750 mg *30 tab |
500 mg *30 tab + 750 mg *60 tab |
|
Tab. Pyridoxine |
50/100 mg |
50 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
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Type B box |
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Use in IP |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
|
Inj. Kanamycin |
15mg/kg/day |
500 mg *24 inj. |
750 mg * 24 inj. |
750 mg *24 inj. |
1000 mg *24 inj. |
|
Tab. Isoniazid-high dose |
100/ 300 mg |
300 mg *30 tab |
300 mg *60 tab |
300 mg *90 tab |
300 mg *90 tab |
|
Tab. Ethionamide |
125/ 250 mg |
125 mg *30 tab + 250 mg *30 tab |
250 mg *60 tab |
250 mg *90 tab |
250 mg *120 tab |
- PWB for Longer Oral M/XDR-TB Regimen : Constitutes only Type A box as there is no separate IP/CP under this regimen
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Standard PWB |
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Continue till Complete Treatment |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
|
Tab. Levofloxacin |
250 / 500 mg |
250 mg *30 tab |
500 mg *30 tab + 250 mg *30 tab |
500 mg *60 tab |
500 mg *60 tab |
|
Tab. Linezolid# |
600 mg |
600 mg *30 tab# |
600 mg *30 tab |
600 mg *30 tab |
600 mg *30 tab |
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Tab. Clofazimine |
50/ 100 mg |
50 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
100 mg *30 tab |
|
Tab. Cycloserine |
250 mg |
250 mg *30 tab |
250 mg *60 tab |
250 mg *90 tab |
250 mg *120 tab |
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Tab. Pyridoxine |
50/100 mg |
50 mg *30 tab |
50 mg *30 tab |
50 mg *30 tab |
50 mg *30 tab |
|
Bedaquiline bottle |
100 mg |
1 Jar (Jar of 188 tablets for full course) |
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# Tab. Linezolid available in 600 mg only. When prescribed with modified dose of 300 mg Once Daily (OD), patient should be advised to divide the pill in half.
- PWB for H-mono/poly DR-TB Regimen: Constitutes only Type A box as there is no separate IP/CP under this regimen
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Standard PWB |
|
Continue till complete treatment |
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Drugs |
Strength |
16-29 kg |
30-45 kg |
46-70 kg |
>70 kg |
|
Tab. Levofloxacin |
250/ 500 mg |
250 mg *180 tab |
250 mg *180 tab + 500 mg *180 tab |
500 mg *360 tab |
500 mg *360 tab |
|
Tab. Rifampicin |
150/ 300/ 450 mg |
300 mg *180 tab |
450 mg *180 tab |
300 mg *360 tab |
300 mg *360 tab + 150 mg *180 tab |
|
Tab. Ethambutol |
400/ 800 mg |
400 mg *180 tab |
800 mg *180 tab |
400 mg *180 tab + 800 mg *180 tab |
800 mg * 360 tab |
|
Tab. Pyrazinamide |
500/ 750 mg |
50 mg *180 tab |
7750 mg *180 tab + 500 mg *180 tab |
750 mg *180 tab + 500 mg *360 tab |
750 mg *360 tab + 500 mg *180 tab |
|
Tab. Pyridoxine |
50/100 mg |
50 mg *180 tab |
100 mg *180 tab |
100 mg *180 tab |
100 mg*180 tab |
In comparison to other DR-TB regimens, a full treatment course should be prepared for the entire duration of 6 months.
Resources
- Standard Operating Procedure Manual Procurement & Supply Chain Management, CTD, MoHFW,India,2018
- Procurement, Supply Chain Management & Preventive Maintenance, Module 6, CTD, MoHFW, India.
Assessment
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Question |
Answer 1 |
Answer 2 |
Answer 3 |
Answer 4 |
Correct answer |
Correct explanation |
Page id |
Part of Pre-test |
Part of Post-test |
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Which type of drug box is issued to the patient on all oral H-mono/ poly regimen? |
Type A |
Type B |
Type A & Type B |
Type C |
1 |
A patient initiated on all oral H-mono/poly DR-TB regimen will receive the monthly type A box. |
|
Yes |
Yes |
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